Disease Information

CUI  C0002395
Disease Name  Alzheimer's Disease
Synonymous  Alzheimer Disease
Disease, Alzheimer
Alzheimer's disease, NOS
Disease, Alzheimer's
Primary Senile Degenerative Dementia
Dementia, Primary Senile Degenerative
Dementia, Senile
Dementias, Senile
Senile Dementias
Senile Dementia
PRIMARY DEGENERATIVE DEMENTIA
Senile Dementia, Alzheimer Type
SENILE DEMENTIA OF THE ALZHEIMER TYPE
Alzheimer Type Senile Dementia
Dementia, Alzheimer Type
DEMENTIA OF THE ALZHEIMER TYPE
Dementia of the Alzheimer's type
Alzheimer Type Dementia
DAT
SDAT
AD
AD - Alzheimer's disease
DAT - Dementia Alzheimer's type
Dementia in Alzheimer's disease
[X]Dementia in Alzheimer's disease, unspecified
[X]Dementia in Alzheimer's disease
simple senile dementia
Alzheimers Disease
Alzheimers Dementia
[X]Dementia in Alzheimer's disease, unspecified (disorder)
[X]Dementia in Alzheimer's disease (disorder)
Alzheimer's disease (disorder)
Description  A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

neurodegenerative disorder of the CNS resulting in progressive loss of memory and intellectual functions; begins in the middle or later years; characterized by brain lesions such as neurofibrillary tangles and neuritic plaques.

A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.


Gene Information

CUI Disease Gene Symbol Table Name
 C0002395  Alzheimer's disease  HFE  GAD
 C0002395  Alzheimer's disease  HFE  GAD